ALAN EBRINGER, M.B., M.R.A.C.P.; IAN R. MACKAY, M.D., F.R.C.P., F.R.A.C.P.
A 49-year-old woman had pemphigus vulgaris for 8 years. She had been treated for 5 years with prednisolone in increasingly high doses, up to 200 mg daily, and had developed numerous and life-threatening side-effects. She was treated over the last 3 years with cyclophosphamide, 200 mg daily, in four separate courses. This allowed gradual reduction in the high maintenance doses of prednisolone and induced remissions.
EBRINGER A, MACKAY IR. Pemphigus Vulgaris Successfully Treated with Cyclophosphamide. Ann Intern Med. ;71:125–127. doi: 10.7326/0003-4819-71-1-125
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Published: Ann Intern Med. 1969;71(1):125-127.
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