FRANCIS A. BREEN JR., M.D.; JAMES L. TULLIS, M.D.
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To the Editor: We would like to take this opportunity to clarify an important aspect of our paper "Ethanol Gelation: A Rapid Screening Test for Intravascular Coagulation" (Ann. Intern. Med. 69: 1197, 1968).
We mentioned that the anticoagulant used was 0.1 M buffered citrate but did not emphasize the importance of using only a buffered citrate. The product we used was Special Anticoagulant Solution (Hyland Laboratories, Los Angeles) as provided with the partial thromboplastin-time kit. This provides the plasma drawn into it with a pH of approximately 7.30. Other anticoagulants such as AGD or oxalate produce a more alkaline pH,
BREEN FA, TULLIS JL. ETHANOL GELATION TEST IMPROVED. Ann Intern Med. 1969;71:433–434. doi: 10.7326/0003-4819-71-2-433_2
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Published: Ann Intern Med. 1969;71(2):433-434.
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