WILLIAM M. MCCONAHEY, M.D.
In a recent French paper, Itelson, Rubinstein, Gaist, and Ménaché (1) reemphasize the previously reported information (2-4) that creatine kinase activity in serum is above normal in patients who have hypothyroidism and below normal in those who have hyperthyroidism. On the basis of these findings they advocate the measurement of serum creatine kinase as a diagnostic "screening test" of thyroid function. The diagnostic potential of this test appears to be greater in hypothyroidism than in hyerpthyroidism because the mean level in the former is about eight times the normal mean but in the latter only about one half the normal
MCCONAHEY WM. Serum Creatine Kinase as a Test of Thyroid Function. Ann Intern Med. ;71:1022–1023. doi: 10.7326/0003-4819-71-5-1022
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Published: Ann Intern Med. 1969;71(5):1022-1023.
Endocrine and Metabolism, Thyroid Disorders.
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