M. DAVID POSNER, M.D.
To the editor: The superb article by Giraldo, Blumenthal, and Spink, "Aspirin Intolerance and Asthma" (Ann Intern Med 71:479, 1969) influences me to ask—are you measuring a possible allergic phenomenon or are you measuring your measurements? More simply, are the tests you used—within their limits—capable of measuring aspirin or other drug allergy? For example, would you obtain a 100% of statistically significant differences if you were to test 100 people with known immediate reactions to, say, penicillin and to a variety of other drugs?
This question of whether and to what extent the standard (and the quantitative limits traditionally accepted)
M. DAVID POSNER. Measuring Aspirin Allergy. Ann Intern Med. 1970;72:147. doi: 10.7326/0003-4819-72-1-147_1
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Published: Ann Intern Med. 1970;72(1):147.
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