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Spasmophilia, a term rarely encountered in the English medical literature, is defined by Dr. J. Durlach as a "constitutional state of neuromuscular hyperexcitability . . . detected either through Chvostek's sign or the electromyographic criterion. . . ." He proceeds to describe spasmophilia as a nosological entity related to intracellular magnesium deficit. Symptoms of spasmophilia are many (central, peripheral, autonomic, and trophic) and "all of them nonspecific." The diagnostic criteria are based on Chvostek's sign, myoelectric abnormalities, and more recently described abnormalities of the electronystagmogram. Although data are presented that indicate statistical differences between group means for plasma magnesium (even
Spasmophilia and Magnesium Deficit.. Ann Intern Med. ;72:298–299. doi: 10.7326/0003-4819-72-2-298_3
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Published: Ann Intern Med. 1970;72(2):298-299.
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