ARTHUR A. COHEN, M.D.; PAUL M. STEVENS, M.D., F.A.C.P.; S. DONALD GREENBERG, M.D.; GERALD M. LEMOLE, M.D.
A patient with massive unilateral pulmonary fibrosis showed pathological evidence of dense organized fibrous tissue with patent pulmonary arteries and veins traversing the areas of dense fibrosis. A few of the bronchioles were occluded with organized fibrous tissue, although most were patent. Preoperative physiologic evaluation showed hypoxemia and pulmonary hypertension. Pulmonary angiograms demonstrated decreased but definite perfusion of the fibrotic lung which was undetected by radioisotopic techniques. Resection of the fibrotic lung was associated with a significant improvement in arterial oxygen tension and a lowering of the pulmonary artery pressure.
COHEN AA, STEVENS PM, GREENBERG SD, LEMOLE GM. Massive Unilateral Pulmonary Fibrosis: Clinical, Physiologic, and Morphologic Studies. Ann Intern Med. ;72:537–542. doi: 10.7326/0003-4819-72-4-537
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Published: Ann Intern Med. 1970;72(4):537-542.
Interstitial Lung Disease, Pulmonary/Critical Care.
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