MAVLIGIT GIORA, M.D.
To the editor: Dr. Omenn (January 1970 issue of the ANNALS) outlined the various polypeptide hormones known to be ectopically produced, with the associated paraneoplastic syndromes. It seems as if one hormone was inadvertently left out, namely, growth hormone. I would like to draw attention to a case reported by Steiner, Dahlbäck, and Waldenström (1) in which adenocarcinoma of the left lung was associated with acromegaloid traits and typical hypertrophic osteoarthropathy. The fasting plasma growth hormone level was very high (38 ng/ml), and it came back to normal (3.5 ng/ml) after resection of the tumor. Although tumor tissue was not
GIORA M. Ectopic Polypeptide Hormone Production By Tumors. Ann Intern Med. ;72:604. doi: 10.7326/0003-4819-72-4-604
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Published: Ann Intern Med. 1970;72(4):604.
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