GRAZIANI GIORGIO, M.D.; PONTICELLI CLAUDIO, M.D.; DI FILIPPO GEMMA, M.D.; REDAELLI BRUNO, M.D.
To the editor: In their article, "Acid-Base Status During the Interdialytic Period in Patients Maintained with Chronic Hemodialysis" (Ann Intern Med 71:1105-1111, 1969) Rosenbaum and co-workers stress the difficulty in interpreting the considerable hypocapnia always found at the end of the hemodialysis. For most authors it is due to the hyperventilation caused by persistent acidosis. In our opinion the remarkable diffusibility of CO2 across the dialyzing membrane should be considered in the interpretation of this phenomenon.
We have examined the arteriovenous difference of PCO2 by drawing blood at the entrance and at the exit of the dialyzer in a recent
GIORGIO G, CLAUDIO P, GEMMA DF, BRUNO R. Hemodialytic Hypocapnia. Ann Intern Med. ;72:757–758. doi: 10.7326/0003-4819-72-5-757
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Published: Ann Intern Med. 1970;72(5):757-758.
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