Leslie Baer, M.D.; Sheldon C. Sommers, M.D.; Manuel Z. Torres, M.D.; John H. Laragh, M.D., F.A.C.P.
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Twenty-three patients with the clinical picture of primary aldosteronism underwent adrenal surgery at the Presbyterian Hospital, New York, N.Y., between 1959 and 1969. Twelve of these patients had an isolated adrenal cortical adenoma typical of primary aldosteronism, but the other 11 had diffuse nonadenomatous adrenal cortical disease. Removal of the adenoma resulted in an 83% cure rate of hypertension. In contrast, none of the patients who had nonadenomatous disease became normotensive after partial or even total adrenalectomy. Nonadenomatous adrenal disease with hyperaldosteronism is an entity basically different from primary aldosteronism due to a single adenoma, because in the former group
Baer L, Sommers SC, Torres MZ, Laragh JH. Pseudoprimary Aldosteronism.. Ann Intern Med. ;72:788. doi: 10.7326/0003-4819-72-5-788_3
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Published: Ann Intern Med. 1970;72(5):788.
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