George A. Bray, M.D., F.A.C.P.
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Samples of adipose tissue were obtained at surgery or from open biopsies in obese patients. Fat cells were prepared by incubating pieces of fat at 37 C in a buffer containing collagenase. Fifty to 150 fat cells were measured with a binocular microscope using an ocular micrometer. The mean diameter of fat cells from 13 samples of normal fat was 74.7 ± 3.3 µ with a range of 61 to 90 µ. In samples from 10 obese patients the mean diameter was 107.6 ± 3.9 µ with a range of 90 to 128 µ. In four aliquots from the same
Bray GA. Measurement of Human Fat Cells by a New Technique.. Ann Intern Med. ;72:790. doi: 10.7326/0003-4819-72-5-790_4
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Published: Ann Intern Med. 1970;72(5):790.
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