J. A. Reinarz, M.D., F.A.C.P.; M. A. Apicella, M.D.; C. Ellenbogen, M.D.; B. T. Fields Jr., M.D.
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Numerous reports attest to the low mortality and benignancy of appropriately treated meningococcal disease (MD). Recent data suggest that susceptibles lack serum antibody presumably because of no prior antigenic exposure. In 1969, 18 patients with MD were diagnosed. Mortality was 22%, all with shock and disseminated intravascular coagulopathy. However, significant complications occurred in 66% and included pericarditis and tamponade (two), myocarditis (eight), meningococcal pneumonia (two), septic arthritis (one), delayed resolution and severe organic brain syndrome (one), and subarachnoid hemorrhage (one). Meningitis was present in 50% on admission. All were promptly treated with high doses of penicillin and close monitoring of
Reinarz JA, Apicella MA, Ellenbogen C, Fields BT. Meningococcal Disease Due to Virulent Group C Organisms.. Ann Intern Med. ;72:797. doi: 10.7326/0003-4819-72-5-797_3
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Published: Ann Intern Med. 1970;72(5):797.
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