K. Chakko Kuruvila, M.D.; Kathryn L. Popowniak, M.D.; Satoru Nakamoto, M.D.
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Two children with the hemolytic-uremic syndrome were treated by exchange transfusions and hemodialysis, with a dramatic improvement in the clinical picture, reversal of the hematological and neurological abnormalities, and a return of renal function to normal.
The children, aged 3 and 2½ years, respectively, presented with similar clinical features. The initial symptoms were diarrhea and vomiting, followed by oliguria progressing to anuria, gastrointestinal and cutaneous hemorrhage, convulsions, stupor, and coma.
The laboratory findings in the two patients were (respectively): hemoglobin, 8.3 and 8.6 g/100 ml; reticulocyte count, 4.4 and 7.5%; platelet count, 30,000 and 50,000 mm3; and blood urea nitrogen
Kuruvila KC, Popowniak KL, Nakamoto S. Successful Treatment of the Hemolytic-Uremic Syndrome by Exchange Blood Transfusion and Hemodialysis.. Ann Intern Med. ;72:804. doi: 10.7326/0003-4819-72-5-804_2
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Published: Ann Intern Med. 1970;72(5):804.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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