A. L. Thompson Jr., M.D.; R. R. Durrett, M.D.; R. R. Robinson, M.D., F.A.C.P.
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The clinical significance of orthostatic proteinuria is undetermined. It has been suggested that "fixed" orthostatic proteinuria represents an early manifestation of renal disease. A long-term clinical study of 64 young men with fixed orthostatic proteinuria was initiated in 1959. The study was designed to establish the natural history and clinical significance of fixed orthostatic proteinuria. The 5-year follow-up evaluation in 1964 showed some form of clinical proteinuria still apparent in 70% of the patients.
Follow-up contact was made with 58 of 64 patients. Complete evaluations was accomplished in 43 patients. Renal function and protein excretion patterns were studied. Twenty-one of
Thompson AL, Durrett RR, Robinson RR. Fixed Orthostatic Proteinuria: Results of 10-Year Follow-up.. Ann Intern Med. ;72:804–805. doi: 10.7326/0003-4819-72-5-804_5
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Published: Ann Intern Med. 1970;72(5):804-805.
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