MAURICE GROSS, M.D., M.R.C.P.
Serial blood pressure recordings were made over 24-hr periods in 75 men with ischemic cerebrovascular disease in different arterial territories and in 25 controls, using an automatic monitor. A diurnal rhythm of pressure occurred that was similar in patients with cerebrovascular disease and in controls. Pressures were significantly higher in cerebrovascular disease than in controls, and the significant difference was due to the contribution from patients with vertebrobasilar ischemia rather than carotid ischemia. The level of basal pressures was proportional to the level of average daytime pressures in subjects with cerebrovascular disease and in controls. No evidence of exaggerated swings of diurnal pressure was found in subjects with cerebrovascular disease compared with controls to explain the pathogenesis of ischemic episodes, or result from them. Considerably higher than average changes in diurnal pressure were well tolerated in some subjects with major extracranial vascular obstruction without cerebral ischemia developing.
MAURICE GROSS. Diurnal Blood Pressure Variations in Cerebrovascular Disease. Ann Intern Med. 1970;72:823–833. doi: 10.7326/0003-4819-72-6-823
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Published: Ann Intern Med. 1970;72(6):823-833.
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