JONATHAN G. GREENWALD, M.D.
To the editor: In an excellent review of the association between oral contraceptives and cerebrovascular disease, Masi and Dugdale (Ann Intern Med 72:111-121, 1970) note that some of the patients reported had conditions predisposing to stroke (1). The importance of identifying those preexisting disorders that make a woman unsuitable for oral contraception has been recently underscored by the attention "the pill" has received in Senate subcommittee hearings. That the sickling hemoglobinopathy may be one of these is suggested by the following account.
A 20-year-old negro woman, gravida 1, para 1, was admitted to Norwalk Hospital in March 1969 after losing
GREENWALD JG. Stroke, Sickle Cell Trait, and Oral Contraceptives. Ann Intern Med. ;72:960. doi: 10.7326/0003-4819-72-6-960_1
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Published: Ann Intern Med. 1970;72(6):960.
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