SHELDON JACOBSON, M.D.
To the editor: In the article entitled "The Renal Clearance of Amylase in Renal Insufficiency, Acute Pancreatitis and Macroamylasemia" (Ann Intern Med 71:919-925, 1969), Levett, Rapoport, and Cooperband have shown a significant increase in the renal clearance of amylase in acute pancreatitis pari passu with a decrease in creatinine clearance. They were somewhat at a loss to explain this phenomenon, but they felt that a decreased renal tubular reabsorption of amylase or a saturation of tubular reabsorption was unlikely since in some patients the serum amylase was normal when the clearance of amylase was increased.
From several recent studies it
JACOBSON S. Amylase in Renal Failure. Ann Intern Med. ;73:142. doi: 10.7326/0003-4819-73-1-142_1
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Published: Ann Intern Med. 1970;73(1):142.
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