HARRY C. SHIRKEY, M.D.
Teratogenesis (the production of biological malformations) from therapeutic agents represents an extension of the potential of drugs for adverse reactions but limited to a particular stage of the living organism—specifically, the fetus (1,2). Whenever new drugs are used or older ones used for new purposes, adverse reactions should be expected (3), and teratogenesis is among them. The introduction of lithium salts and their availability now for prescription use in the treatment of affective psychoses (4-6) can be expected to bring, as with any other new drug, some unwanted as well as desired effects.
Drug treatment of women in the first
SHIRKEY HC. Teratogenesis from Lithium Carbonate. Ann Intern Med. 1970;73:336–337. doi: 10.7326/0003-4819-73-2-336
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Published: Ann Intern Med. 1970;73(2):336-337.
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