DENNIS P. BERK, M.D.; THOMAS CHALMERS, M.D., F.A.C.P.
Five cases of ototoxicity associated with the oral administration of neomycin are reported. The absence of renal failure but the presence of low serum antibiotic levels in these cases suggests that with prolonged exposure even minimal absorption can be toxic. Additional observations suggest that the related drug paromomycin may be similarly dangerous.
BERK DP, CHALMERS T. Deafness Complicating Antibiotic Therapy of Hepatic Encephalopathy. Ann Intern Med. 1970;73:393–396. doi: 10.7326/0003-4819-73-3-393
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Published: Ann Intern Med. 1970;73(3):393-396.
Encephalopathy, Gastroenterology/Hepatology, Liver Disease, Neurology.
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