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Under natural conditions polyoma virus infection in mice is very common. Tumor production, on the other hand, is extremely rare. The study of oncogenesis by polyoma virus, therefore, represents a laboratory phenomenon having very little to do with what happens in nature. Nevertheless, viral oncogenesis may be one of the most fertile fields in virology. The monograph by Bernice E. Eddy, including 850 references published mostly within the past decade, illustrates this point.
After a brief historical review and a short discussion on classification the properties of the virus are concisely and precisely described. Polyoma virus, unlike other oncogenic viruses,
Polyoma Virus.. Ann Intern Med. 1970;73:501–502. doi: 10.7326/0003-4819-73-3-501_4
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Published: Ann Intern Med. 1970;73(3):501-502.
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