HERBERT FELLERMAN, M.D.; THEODORE G. DALAKOS, M.D.; DAVID H. P. STREETEN, M.B., D. Phil., F.A.C.P., M.R.C.P.
A patient had obvious clinical features of Cushing's syndrome associated with elevated urinary and plasma 17-hydroxycorticoids (17-OHCS) that resisted suppression by dexamethasone, 2 mg every 6 hr. Left-sided adrenal phlebography was followed by epigastric pain, features of adrenal insufficiency, and a fall in plasma and urinary 17-OHCS, with evidence of suppression of adrenocorticotrophic hormone release by the pituitary. Spontaneous loss of all clinical features of Cushing's syndrome was accompanied by a return of plasma and urinary 17-OHCS to normal levels. It is concluded that the adrenal phlebography fortuitously caused subtotal infarction of the adrenal adenoma with remission of hypercortisolism.
FELLERMAN H, DALAKOS TG, STREETEN DHP. Remission of Cushing's Syndrome After Unilateral Adrenal Phlebography: Apparent Destruction of Adrenal Adenoma. Ann Intern Med. ;73:585–589. doi: 10.7326/0003-4819-73-4-585
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Published: Ann Intern Med. 1970;73(4):585-589.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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