JOHN M. PETERS, M.D.; RAYMOND L. H. MURPHY, M.D.
In our plastic world polyurethanes have achieved great commercial importance. The production of polyurethane involves the combination of chemicals containing two highly reactive isocyanate groups with a polyol. It is during this mixing and foaming process that the isocyanates are evolved into the workroom atmosphere. Depending on plant configuration and ventilation, few or many workers can be exposed. Other significant exposures may occur in industrial chemical laboratories and during repair or cleaning of the equipment. The products are used primarily as cushioning materials (mattresses, pillows, seat cushions, and packing materials), for insulation (thin-walled refrigerators and ovens), for soft toys, and
PETERS JM, MURPHY RLH. Pulmonary Toxicity of Isocyanates. Ann Intern Med. ;73:654–655. doi: 10.7326/0003-4819-73-4-654
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Published: Ann Intern Med. 1970;73(4):654-655.
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