CHARLES D. LEONARD, M.D.; RAYMOND B. NAGLE, M.D.; GARY E. STRIKER, M.D.; RALPH E. CUTLER, M.D., F.A.C.P.; BELDING H. SCRIBNER, M.D.
Clinical and pathological features of oliguric acute glomerulonephritis were reviewed in 29 patients who required temporary or permanent dialysis; they were divided into two groups on the basis of antistreptolysin (ASO) titers. Group A (ASO, 200 or above) contained 10 patients with a mean age of 16. Group B (ASO, less than 200) consisted of 19 patients with a mean age of 53. Strong evidence for a recent streptococcal infection was present in each patient in group A and in no group B patients. Diuresis occurred in nine patients in group A and in only two patients in group B. A proliferative exudative glomerular lesion with or without crescents was present in most group A patients, whereas extensive crescent formation with minimal proliferation of glomerular tufts occurred in most group B patients. Oliguric acute glomerulonephritis appears to be a disorder of varying etiology. The prognosis of patients with proved streptococcal infection was much better than has been thought; for the other patients irreversible renal failure was the rule.
CHARLES D. LEONARD, RAYMOND B. NAGLE, GARY E. STRIKER, RALPH E. CUTLER, BELDING H. SCRIBNER. Acute Glomerulonephritis with Prolonged Oliguria: An Analysis of 29 Cases. Ann Intern Med. 1970;73:703–711. doi: 10.7326/0003-4819-73-5-703
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Published: Ann Intern Med. 1970;73(5):703-711.
Nephrology, Urological Disorders.
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