KEHL MARKLEY, M.D.
The development of an effective pseudomonas vaccine for the prophylaxis of fatal pseudomonas infection in burned patients has been reported by Fisher and his co-workers (1-3). This event is the culmination of a number of various investigations.
In spite of the fact that burned animals are more susceptible to Pseudomonas aeruginosa infections than normal animals (4, 5), their antibody production against chemical antigens (6-8), as well as particulate antigens such as sheep erythrocytes (9) and bacteria (10), rises to the same levels as that observed in normal animals. For this reason active immunization seemed feasible. Specific (5, 11) as well
KEHL MARKLEY. Vaccine Prophylaxis for Pseudomonas Infections. Ann Intern Med. 1971;74:140. doi: 10.7326/0003-4819-74-1-140
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Published: Ann Intern Med. 1971;74(1):140.
Infectious Disease, Vaccines/Immunization.
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