ARTHUR D. FLANAGAN, M.D.
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To the editor: I have read the paper on sodium colistimethate by Dr. Koch-Weser in the June issue of the ANNALS (72:857-868, 1970). The report raises certain questions.
A prospective study of this nature tends to promise a more comprehensive evaluation of relevant patient data than a retrospective review. Thus, is it consistent with this expectation to present as results the statement from a prospective study: "Autopsies were performed after 22 of the 32 deaths that followed an adverse reaction to colistin. In 13 (4.5%) of the 288 colistin-treated patients clinical and pathological evidence suggested that adverse effects of this
FLANAGAN AD. Adverse Effects of Sodium Colistimethate. Ann Intern Med. ;74:143–144. doi: 10.7326/0003-4819-74-1-143
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Published: Ann Intern Med. 1971;74(1):143-144.
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