H. L. DUPONT, M.D.; R. B. HORNICK, M.D., F.A.C.P.; H. S. LEVIN, M.D.; M. I. RAPOPORT, M.D.; T. E. WOODWARD, M.D., F.A.C.P.
Hepatic involvement was appraised in three individuals with Q fever. One patient presented with moderately severe hepatitis without pulmonary involvement, whereas the other two were volunteers participating in a trial to evaluate Q fever vaccine. Findings suggest that liver involvement is common in Q fever and that histologic changes are more striking than blood chemical findings. The case of naturally acquired disease shows the clinical variability of Q fever, as extensive granulomatous hepatic infiltration occurred without detectable pulmonary involvement. Q fever is becoming more prevalent throughout the United States and should be considered in patients whose illness resembles "atypical pneumonia" or "infectious hepatitis."
DUPONT HL, HORNICK RB, LEVIN HS, RAPOPORT MI, WOODWARD TE. Q Fever Hepatitis. Ann Intern Med. ;74:198–206. doi: 10.7326/0003-4819-74-2-198
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Published: Ann Intern Med. 1971;74(2):198-206.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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