KENNETH L. BERGSMAN, M.D.; ELLIS J. VAN SLYCK, M.D.
A 50-year-old patient demonstrated an acute atypical variant of myelofibrosis characterized by diffuse marrow fibrosis, peripheral myeloblastosis, normal erythrocyte morphology, lack of massive splenomegaly, and a rapidly fatal course. Although this variant is rare in comparison with other myeloproliferative disorders, it deserves recognition. We favor the designation "acute myelofibrosis" for this entity.
BERGSMAN KL, VAN SLYCK EJ. Acute Myelofibrosis: An Accelerated Variant of Agnogenic Myeloid Metaplasia. Ann Intern Med. 1971;74:232–235. doi: 10.7326/0003-4819-74-2-232
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Published: Ann Intern Med. 1971;74(2):232-235.
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