JERZY GAJEWSKI, M.D., PH.D.
To the editor: Thrombolytic therapy for peripheral vein thrombosis has recently aroused wide interest (1-3). This approach is considered to be relatively safe, with only mild side effects. Although, theoretically, the significantly enhanced fibrinolytic activity—in the presence of a massive fresh venous thrombosis—could favor pulmonary embolization, in practice this does not seem to be a common complication. The following case, however, indicates that such a complication represents a real possibility:
A 52-year-old saleswoman was admitted to the hospital1 because of marked painful swelling of her right leg. Two days before admission she first noticed moderate pain in the posterior region
GAJEWSKI J. Thrombolytic Therapy and Fatal Massive Pulmonary Emboli. Ann Intern Med. ;74:450. doi: 10.7326/0003-4819-74-3-450_1
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Published: Ann Intern Med. 1971;74(3):450.
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