Saul Genuth, M.D.; LeRoy Klein, M.D.
This content is PDF only. Please click on the PDF icon to access.
This report describes studies of two patients with disseminated Paget's disease of bone who presented a unique opportunity to observe the relationship between disease activity and parathyroid hormone (PTH) effects.
Patient 1 had simultaneous idiopathic hypoparathyroidism. Basal studies showed serum calcium, 5.5 mg/100 ml (ionized 43%); serum phosphorus, 4.8 mg/100 ml; serum PTH, less than 0.2 ng/ml; alkaline phosphatase, 394 IU (normal, 15 to 45 IU); and urinary hydroxyproline, 240 to 260 mg/day (normal, less than 40). After administration of PTH, serum calcium rose to 11.2 mg/100 ml (49% ionized); serum phosphorus fell to 2.5 mg/100 ml, and urinary calcium
Genuth S, Klein L. Independence of Paget's Disease of Bone from Parathyroid Hormone.. Ann Intern Med. ;74:823. doi: 10.7326/0003-4819-74-5-823_4
Download citation file:
Published: Ann Intern Med. 1971;74(5):823.
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use