W. H. R. Nye, M.D., F.A.C.P.; R. P. Eaton, M.D.
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No correlation between insulin secretion and triglyceride concentration has been demonstrated by other investigators in patients with primary endogenous lipemia nor, in our total population of 66 lipemic patients, has any correlation emerged from an analysis of insulin-triglyceride interrelationships. In contrast, the physiological lipemia induced by carbohydrate has been closely correlated with insulin secretion (IRI). It seems plausible that the failure to implicate insulin in abnormal lipemia relates to the simultaneous operation, at cross purposes, of many factors influencing carbohydrate and lipid metabolism. In an attempt to reduce the number of variables we have examined the integrated IRI-triglyceride concentration relationship
Nye WHR, Eaton RP. Demonstration of a Direct Pathophysiological Role for Insulin in Primary Endogenous Lipemia.. Ann Intern Med. ;74:824. doi: 10.7326/0003-4819-74-5-824_3
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Published: Ann Intern Med. 1971;74(5):824.
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