James A. Curtin, M.D., F.A.C.P.
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A clinical and laboratory picture simulating infectious meningitis with hypoglycorrhachia may develop after pantopaque myelography. Three patients with normal cerebrospinal fluid at the time of myelography later developed meningitis. All cultures, including fungus and tuberculosis, were negative. Each patient complained of headache, stiff neck, and two had fever. The myelograms were performed at different times by different people. Twelve days after myelography the first patient had cerebrospinal fluid (CSF) lymphocytosis, elevated protein, and CSF sugar 30 mg/100 ml to blood sugar 75 mg/100 ml. Improvement occurred rapidly after prednisone therapy. The patient was well 18 months later without medication. The
Curtin JA. Pantopaque Hypersensitivity Meningitis.. Ann Intern Med. ;74:838. doi: 10.7326/0003-4819-74-5-838_4
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© 2018
Published: Ann Intern Med. 1971;74(5):838.
DOI: 10.7326/0003-4819-74-5-838_4