Harold L. Israel, M.D., F.A.C.P.; Robert A. Goldstein, M.D.
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Kveim tests in 39 selected patients with sarcoidosis demonstrated that the reaction was related to persistent lymphadenopathy and not to duration or activity of illness. Seventeen asymptomatic patients with marked mediastinal and hilar node enlargement of long duration all reacted strongly. Positive tests occurred in only 3 of 10 patients having disease of recent onset with minimal adenopthy and in only 1 of 12 patients with active hepatic or cutaneous sarcoidosis and normal chest roentgenograms.
The demonstration that the Kveim reaction is more closely related to lymphadenopathy than to granulomatosis led to tests in patients with lymphadenopathy caused by other
Israel HL, Goldstein RA. Relationship of Kveim Reaction to Lymphadenopathy In Sarcoidosis.. Ann Intern Med. ;74:840. doi: 10.7326/0003-4819-74-5-840_2
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Published: Ann Intern Med. 1971;74(5):840.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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