B. B. DIENA, PH.D., M.V.D.
Tuberculosis mortality and morbidity have been impressively reduced by chemotherapy, but in recent years there has been a resurgence of new cases of tuberculosis. Reservoirs of tuberculosis infection are escaping detection because of the inadequacy of mass roentgenography and tuberculin testing. Omran and Deuschule (1), in a controlled study, found an 18% failure rate in the detection of tuberculosis by these methods. Futhermore, tuberculin sensitivity does not equate with active tuberculosis and is of little value after Bacillus Calmette-Guérin (BCG) vaccination. For these reasons, many investigators have tried to develop a serological method for the diagnosis of mycobacterial infections, and
DIENA BB. Problems in the Serodiagnosis of Tuberculosis. Ann Intern Med. ;75:132–134. doi: 10.7326/0003-4819-75-1-132
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Published: Ann Intern Med. 1971;75(1):132-134.
Infectious Disease, Mycobacterial Infections.
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