ROBERT S. HOLZMAN, M.D.; FREDERIC BISHKO, M.D.
Four heroin addicts developed hematogenous osteomyelitis with indolent courses. In three, characteristic X-ray changes evolved during their hospital stays. Only one had a positive blood culture. The infecting organisms were not characteristic of those found in spontaneously occurring hematogenous osteomyelitis but rather reflected the spectrum of pathogens that infect those addicted to narcotics: staphylococci, Gram-negative rods, and yeasts. In such patients early surgical exploration is necessary to establish an accurate bacteriologic diagnosis.
HOLZMAN RS, BISHKO F. Osteomyelitis in Heroin Addicts. Ann Intern Med. ;75:693–696. doi: 10.7326/0003-4819-75-5-693
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Published: Ann Intern Med. 1971;75(5):693-696.
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