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Rubella is generally a mild illness, but when the infection is acquired by a woman early in pregnancy, particularly in the first 3 months, fetal infection with subsequent abnormalities often develops. Preventing infection of the fetus and the resulting congenital rubella syndrome is the principal objective of rubella control.
Live, attenuated rubella virus vaccine1 is a highly effective immunizing agent, and its use provides the first suitable method of preventing rubella. Although it is safe and protective for children, because of the possible risk of vaccine virus for the fetus, its safety for pregnant women has not been determined. The
Rubella Virus Vaccine: Recommendation of the Public Health Service Advisory Committee on Immunization Practices. Ann Intern Med. ;75:757–759. doi: 10.7326/0003-4819-75-5-757
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Published: Ann Intern Med. 1971;75(5):757-759.
Infectious Disease, Prevention/Screening, Vaccines/Immunization.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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