On 14 November 1921 Frederick G. Banting and Charles H. Best announced to their colleagues at a regular meeting of the Physiological Journal Club of the University of Toronto (1) that they had been able to demonstrate, in laboratory experiments begun in May,
an antidiabetic principle in extracts of dog's pancreas and in fetal calf pancreas.
Not surprisingly, they soon faced
two great pressures. . . . One was exerted by the diabetic patients who needed insulin. After the announcement of our findings . . . the forerunner of the thousands of letters from diabetics appeared and soon patients, many
H. E. Insulin: Fifty Years Ago. Ann Intern Med. ;75:797–800. doi: 10.7326/0003-4819-75-5-797
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Published: Ann Intern Med. 1971;75(5):797-800.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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