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The title would imply a discussion on anticoagulants; as expected for a "handbuch," however, the subject is treated as part of an exhaustive review of the chemistry and pharmacology of blood coagulation. This broad look at anticoagulants is divided into four sections written by authorities well known in this country. Dr. Mammen describes the physiology of blood coagulation, detailing the chemistry of the known procoagulants individually and the theoretical considerations with regard to prothrombin activation. The most recent work of Seegers on prothrombin derivatives is discussed in addition to the enzyme activation or cascade theory. The author attempts to relate
Anticoagulantien.. Ann Intern Med. 1971;75:827. doi: 10.7326/0003-4819-75-5-827_1
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Published: Ann Intern Med. 1971;75(5):827.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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