JOSEPH G. SINKOVICS, M.D., F.A.C.P.
To the editor: The critical review of intraendothelial inclusions inclusions by Tisher and colleagues (Ann Intern Med 75:537-547, 1971) certainly deserves compliments. In a report to appear soon (1) we agree that the prevalence of these structures in systemic lupus erythematosus (SLE) is highly significant and of great diagnostic value. However, the inclusions occur in lymphoid cells as well (1); thus the term "intraendothelial" should not be applied generally.
Two further comments are appropriate. When Tisher and colleagues state that these inclusions "bear little resemblance to any of these known viruses" and give the diameters of myxoviruses and paramyxoviruses as
SINKOVICS JG. Intraendothelial Inclusions in Systemic Lupus Erythematosus. Ann Intern Med. 1972;76:142–143. doi: 10.7326/0003-4819-76-1-142
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Published: Ann Intern Med. 1972;76(1):142-143.
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