KONG-OO GOH, M.D.
The conventional classification of leukemias is based on the morphological cell lines (myelocytic, lymphocytic, monocytic) and the clinical course of the disease (acute or chronic). Greater precision has been added recently to diagnosis of certain leukemias by use of cytogenetic techniques. There is a close relation between the acuteness of the disease and the involvement of the immature cell types. The morphologic division is rarely sharp; mixed components are frequently seen. Most of the leukemias maintain the original cell line during recurrence of the disease after a remission. In some cases, however, different stem cells or younger cells become involved,
GOH K. Classifying Acute Leukemias. Ann Intern Med. ;76:325–326. doi: 10.7326/0003-4819-76-2-325
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Published: Ann Intern Med. 1972;76(2):325-326.
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