JAMES C. MELBY, M.D.
This content is PDF only. Please click on the PDF icon to access.
To the editor: Dr. M. H. Maxwell states in the UCLA Conference, "Hypertension—Primary and Secondary" (Ann Intern Med 75:761-776, 1971), that "about 20% of all patients with so-called essential hypertension have suppressed plasma renin activity. This has been unexplained, but it is exciting that investigators are finding that most of these patients have an excess of 18-hydroxydeoxycorticosterone." Although Dr. Maxwell does not refer specifically to the published evidence for this assertion, my colleagues and I have, for the past few years, been measuring metabolites of 18-OH-DOC in the urine of patients with low renin hypertension and find that not more
MELBY JC. Excess 18-Hydroxydeoxycorticosterone: Most or Some?. Ann Intern Med. 1972;76:334. doi: 10.7326/0003-4819-76-2-334_1
Download citation file:
Published: Ann Intern Med. 1972;76(2):334.
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use