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In spite of the methodologic difficulties in doing genetic research in psychiatry, it is hard to deny that there are genetic factors in schizophrenia, and in this new monograph Slater and Cowie review the classic literature on the genetics of schizophrenia. In the six older twin studies, 58% to 69% of monozygote twin pairs are concordant for schizophrenia, in contrast to 0 to 18% of dizygotic twin pairs. This finding is verified by the four more recent studies, but the results are less striking. If one includes borderline psychotic twins, the monozygotic concordance rate was 36% to 50%, in contrast
The Genetics of Mental Disorders.. Ann Intern Med. ;76:529–530. doi: 10.7326/0003-4819-76-3-529_3
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Published: Ann Intern Med. 1972;76(3):529-530.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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