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"In patients with achalasia, lower esophageal sphincter (LES) dysfunction plays an important role in the impairment of esophageal emptying. To evaluate this dysfunction, the manometric characteristics of the LES were recorded for 20 normals and for 16 patients with achalasia, both before and after pneumatic dilation. Before dilation, patients with achalasia have two abnormalities in LES function: (1) LES pressure at rest is twice that recorded in normals; and (2) the LES does not relax to the level of gastric pressure during swallowing. Therefore, a residual LES pressure is always present in patients with achalasia. Following clinically successful pneumatic dilation,
Scene in Print: More About the LES. Ann Intern Med. ;76:675. doi: 10.7326/0003-4819-76-4-675_4
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Published: Ann Intern Med. 1972;76(4):675.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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