KARL D. NOLPH, M.D., F.A.C.P.
A recent British paper (1) has described studies of Slow Sodium®1, a tablet preparation of sodium chloride in a wax-sponge formulation, which can be ingested rapidly with minimal gastrointestinal disturbance, presumably because of slow release of electrolytes from the tablets. Each 600-mg tablet contains 10 mmoles [10 mEq] of sodium and is totally absorbed over 6 hours. As much as 200 mmoles [200 mEq] per 10 minutes and 500 mmoles [500 mEq] per day of sodium can be tolerated orally. Slow Sodium was shown to prevent sodium depletion due to salt-losing nephritis, unwanted hemodialysis ultrafiltration, and sweat losses with strenuous
NOLPH KD. "Slow Sodium": Double-Edged Drug. Ann Intern Med. ;76:825. doi: 10.7326/0003-4819-76-5-825_1
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Published: Ann Intern Med. 1972;76(5):825.
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