JOHN I. GALLIN, M.D.; DONALD KAYE, M.D.; WILLIAM M. O'LEARY, PH.D.
To the editor: We are writing in reference to the article, "Gram-Negative Sepsis: Detection of Endotoxemia with the Limulus Test" (Ann Intern Med 76:1-7, 1972), by Levin and associates, who reported slightly elevated mean serum free fatty acids and normal mean triglycerides in patients with "Gram-negative sepsis." They contrasted these results to our studies (1) in which total serum lipids, free fatty acids, and triglycerides were significantly elevated in patients with Gram-negative bacteremia compared with other groups, including healthy controls and patients with bacteremia caused by Gram-positive cocci. We found that free fatty acids were usually elevated early (usually within
GALLIN JI, KAYE D, O'LEARY WM. Endotoxin and Lipids. Ann Intern Med. ;76:831–832. doi: 10.7326/0003-4819-76-5-831
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Published: Ann Intern Med. 1972;76(5):831-832.
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