GERALD P. RODNAN, M.D.; THOMAS G. BENEDEK, M.D.
To the editor: Since completing our paper on the early history of synovia (1), we have discovered the following passage from Galen's commentaries on Hippocrates (2), which contains what appears to be the earliest reference to clinical examination of the joint fluid.
Hippocrates: One must perform an examination when there is no pus in the joints to find what is in them. Galen: Sabinus [apparently a contemporary of Galen] has written thusly. However, most transcribe these words according to the following text: "One must perform an examination whether there is not pus in the joints to find what is in
RODNAN GP, BENEDEK TG. Hippocrates, Galen, and Synovia. Ann Intern Med. ;76:834–835. doi: 10.7326/0003-4819-76-5-834_3
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Published: Ann Intern Med. 1972;76(5):834-835.
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