Robert A. Good, M.D., Ph.D.
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Studies of immunological development in both ontogenetic and phylogenetic perspective supported and often guided by studies of patients with immunodeficiency have given much insight into the organization and function of the immunologic apparatus. Basically, the lymphoid system is organized into two interacting systems of lymphoid cells. One system develops under the differentiative influence of the thymus, the other in birds under the differentiative influence of the bursa of Fabricius. The thymusdependent system cells subserve the functions of cell-mediated immunities. These include delayed allergy; much of solid tissue allograft rejection capacity to initiate graft-versus-host reactions; and a major specific component in
Good RA. Developmental Aspects of Immunity.. Ann Intern Med. ;76:853–854. doi: 10.7326/0003-4819-76-5-853_5
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Published: Ann Intern Med. 1972;76(5):853-854.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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