H. Sherwood Lawrence, M.D., F.A.C.P.
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Transfer factor is one of the most potent immunologic reagents available for the induction and reconstitution of delayed-type hypersensitivity and cellular immunity in humans. It is a small (less than 10 000 mw), nonantigenic, nonimmunoglobulin moiety that is separated from other macromolecules in human blood leukocytes by dialysis and concentrated by lyophilization of the dialysate. Dialysable transfer factor possesses all of the immunological properties of the viable leukocytes from which it is prepared-namely, for prolonged periods (1 to 2 years) transfer factor gives the recipient each of the specific delayed-type hypersensitivity responses and cellular immunities possessed by the donor.
Lawrence HS. Transfer Factor and Cellular Immune Deficiency Diseases.. Ann Intern Med. 1972;76:854. doi: 10.7326/0003-4819-76-5-854_1
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Published: Ann Intern Med. 1972;76(5):854.
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