Robert B. Talley, M.D., F.A.C.P.; Marc F. Laventurier, B. S.
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Drug-drug interactions have been reported to be clinically significant and to have an adverse effect on the course of treatment. The frequency of such events has not been quantified. The drug universe of 45 000 Medi-Cal patients has been challenged through electronic data processing techniques for instances of well-documented major therapeutic interactions. A file of 328 473 prescriptions dispensed in a time frame of over 8 months showed that approximately 15 000 prescriptions that could be considered drug interactions were eliminated. The incidence and the clinical significance of some major potential interactions were assayed for outcomes and relevance for various
Talley RB, Laventurier MF. The Incidence of Drug-Drug Interactions in a Medi-Cal Population.. Ann Intern Med. ;76:857. doi: 10.7326/0003-4819-76-5-857_1
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Published: Ann Intern Med. 1972;76(5):857.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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