David S. Janowsky, M.D.; Steven Berens, M.D.; John M. Davis, M.D.
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A correlation between premenstrual-menstrual mood changes, weight changes, and alterations in the aldosterone-dependent urinary potassium-to-sodium ratio during the menstrual cycle was studied. Eleven female college-age volunteers were studied on a metabolic ward for a total of 410 days during which time 14 menses occurred. Daily negative-affect self-ratings, preprandial postvoiding morning weights, and 24-hour urinary collections were obtained and analyzed for potassium-to-sodium ratios. All subjects were placed on a constant caloric intake and a 100 mEq/day sodium chloride diet and housed on a metabolic ward. Data analysis showed a significant positive correlation between the subject groups' negative affect for a given
Janowsky DS, Berens S, Davis JM. Correlations Between Mood, Urinary Electrolytes, and Weight During the Menstrual Cycle.. Ann Intern Med. ;76:858. doi: 10.7326/0003-4819-76-5-858_3
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Published: Ann Intern Med. 1972;76(5):858.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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