Martin S. Kleinman, M.D., F.A.C.P.; Michael D. Turner, M.D.
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A radioimmunoassay system was developed for the carcinoembryonic antigen of the digestive tract, using a highly purified radioactive antigen. This was used for the assay of serum specimens from 105 patients. Fourteen normal control subjects had a mean serum carcinoembryonic antigen of 1.6 ng/ml. In forty-three patients with proved cancer of the rectum or colon it was possible to classify the state of the disease by a modification of the classification proposed by Dukes. The mean serum carcinoembryonic antigen in these 43 patients was 11.2 ng/ml. Of the 43 patients, 10 were classified as stage A, 8 as stage B,
Kleinman MS, Turner MD. The Relationship of Serum Carcinoembryonic Antigen to the Stage of the Disease in Patients with Carcinoma of the Colon.. Ann Intern Med. ;76:860. doi: 10.7326/0003-4819-76-5-860_1
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Published: Ann Intern Med. 1972;76(5):860.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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