Otto T. Nebel; Donald O. Castell
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Although symptoms of gastroesophageal reflux often occur after eating, changes in lower esophageal sphincter strength after the ingestion of foods have received little attention. Recent data from this laboratory indicate that consistent increases in sphincter pressure follow a protein meal, whereas fat meals are followed by significant decreases in pressure. The interrelationship of these two basic foods was tested in normal subjects, using an infused open-tipped system to continuously record sphincter pressure. Test meals consisted of 150-calorie quantities of protein or fat in a volume of 150 ml. In addition, a 300-calorie meal of equal calorie quantities of protein and
Nebel OT, Castell DO. Fat Inhibition of the Lower Esophageal Sphincter: A Mechanism for Fatty Food Intolerance.. Ann Intern Med. ;76:860. doi: 10.7326/0003-4819-76-5-860_3
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Published: Ann Intern Med. 1972;76(5):860.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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